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Supplemental Information

Screen Description

Solubility and Stability Screen 3

Buffer Screens / Solubility and Stability Screen 3
Created 2024-12-06.

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Solubility and Stability Screen 3

  • Z0001876 Lot 1 (1500.0 µl)

Screen Structure

Solubility and Stability Screen 3

Well Count 96
Number of distinct ingredients 28
Internal diversity (score mean dist) 0.985

Screen Composition

2025-08-15T21:11:49.735590 image/svg+xml Matplotlib v3.10.5, https://matplotlib.org/
ingredient type Solubility and Stability Screen 3
Buffer 15
Cryoprotectant 9
Organic (non-volatile) 18
Organic (volatile) 3
Salt 27

Well Contents

Buffers are shown in italics. More information about buffers.
Primary factors are shown in bold. More information about primary factors.
Solubility and Stability Screen 3 Well Contents  🔍
WellIngredient, Concentration, Units, pHpHRecipe 1000μl
A1NA
1000.0 μl of water (100 v/v)
A2NA
1000.0 μl of water (100 v/v)
A3NA
1000.0 μl of water (100 v/v)
A4
  • arg-glu BCC 0.1 M -
NA
100.0 μl of arg-glu BCC (1 M)
900.0 μl of water (100 v/v)
A5
  • arg-glu BCC 0.2 M -
NA
200.0 μl of arg-glu BCC (1 M)
800.0 μl of water (100 v/v)
A6
  • arg-glu BCC 0.3 M -
NA
300.0 μl of arg-glu BCC (1 M)
700.0 μl of water (100 v/v)
A7
  • arginine BCC 0.1 M -
NA
200.0 μl of arginine BCC pH 7 (0.5 M)
800.0 μl of water (100 v/v)
A8
  • arginine BCC 0.2 M -
NA
400.0 μl of arginine BCC pH 7 (0.5 M)
600.0 μl of water (100 v/v)
A9
  • arginine BCC 0.3 M -
NA
600.0 μl of arginine BCC pH 7 (0.5 M)
400.0 μl of water (100 v/v)
A10NA
1000.0 μl of water (100 v/v)
A11NA
1000.0 μl of water (100 v/v)
A12NA
1000.0 μl of water (100 v/v)
B1
  • glycine BCC 0.1 M -
NA
100.0 μl of glycine BCC (1 M)
900.0 μl of water (100 v/v)
B2
  • glycine BCC 0.3 M -
NA
300.0 μl of glycine BCC (1 M)
700.0 μl of water (100 v/v)
B3
  • glycine BCC 0.5 M -
NA
500.0 μl of glycine BCC (1 M)
500.0 μl of water (100 v/v)
B4
  • histidine BCC 0.05 M -
NA
100.0 μl of histidine BCC (0.5 M)
900.0 μl of water (100 v/v)
B5
  • histidine BCC 0.125 M -
NA
250.0 μl of histidine BCC (0.5 M)
750.0 μl of water (100 v/v)
B6
  • histidine BCC 0.2 M -
NA
400.0 μl of histidine BCC (0.5 M)
600.0 μl of water (100 v/v)
B7
  • glucose BCC 0.25 M -
NA
250.0 μl of glucose BCC (1 M)
750.0 μl of water (100 v/v)
B8
  • glucose BCC 0.5 M -
NA
500.0 μl of glucose BCC (1 M)
500.0 μl of water (100 v/v)
B9
  • glucose BCC 1 M -
NA
1000.0 μl of glucose BCC (1 M)
B10
  • trehalose BCC 0.25 M -
NA
250.0 μl of trehalose BCC (1 M)
750.0 μl of water (100 v/v)
B11
  • trehalose BCC 0.5 M -
NA
500.0 μl of trehalose BCC (1 M)
500.0 μl of water (100 v/v)
B12
  • trehalose BCC 1 M -
NA
1000.0 μl of trehalose BCC (1 M)
C1
  • D-Sorbitol BCC 0.5 M -
NA
250.0 μl of D-Sorbitol BCC (2 M)
750.0 μl of water (100 v/v)
C2
  • D-Sorbitol BCC 1 M -
NA
500.0 μl of D-Sorbitol BCC (2 M)
500.0 μl of water (100 v/v)
C3
  • D-Sorbitol BCC 2 M -
NA
1000.0 μl of D-Sorbitol BCC (2 M)
C4
  • triethylene glycol BCC 5 v/v -
NA
50.0 μl of triethylene glycol BCC (100 v/v)
950.0 μl of water (100 v/v)
C5
  • triethylene glycol BCC 10 v/v -
NA
100.0 μl of triethylene glycol BCC (100 v/v)
900.0 μl of water (100 v/v)
C6
  • triethylene glycol BCC 20 v/v -
NA
200.0 μl of triethylene glycol BCC (100 v/v)
800.0 μl of water (100 v/v)
C7
  • glycerol BCC 10 v/v -
NA
125.0 μl of glycerol BCC (80 v/v)
875.0 μl of water (100 v/v)
C8
  • glycerol BCC 20 v/v -
NA
250.0 μl of glycerol BCC (80 v/v)
750.0 μl of water (100 v/v)
C9
  • glycerol BCC 50 v/v -
NA
625.0 μl of glycerol BCC (80 v/v)
375.0 μl of water (100 v/v)
C10
  • ethylene glycol BCC 5 v/v -
NA
50.0 μl of ethylene glycol BCC (100 v/v)
950.0 μl of water (100 v/v)
C11
  • ethylene glycol BCC 10 v/v -
NA
100.0 μl of ethylene glycol BCC (100 v/v)
900.0 μl of water (100 v/v)
C12
  • ethylene glycol BCC 20 v/v -
NA
200.0 μl of ethylene glycol BCC (100 v/v)
800.0 μl of water (100 v/v)
D1
  • urea BCC 0.1 M -
NA
40.0 μl of urea BCC (2.5 M)
960.0 μl of water (100 v/v)
D2
  • urea BCC 0.3 M -
NA
120.0 μl of urea BCC (2.5 M)
880.0 μl of water (100 v/v)
D3
  • urea BCC 0.5 M -
NA
200.0 μl of urea BCC (2.5 M)
800.0 μl of water (100 v/v)
D4
  • choline dihydrogen phosphate BCC 4 w/v -
NA
80.0 μl of choline dihydrogen phosphate BCC (50 w/v)
920.0 μl of water (100 v/v)
D5
  • choline dihydrogen phosphate BCC 8 w/v -
NA
160.0 μl of choline dihydrogen phosphate BCC (50 w/v)
840.0 μl of water (100 v/v)
D6
  • choline dihydrogen phosphate BCC 20 w/v -
NA
400.0 μl of choline dihydrogen phosphate BCC (50 w/v)
600.0 μl of water (100 v/v)
D7
  • NDSB 221 BCC 0.25 M -
NA
166.7 μl of NDSB 221 BCC (1.5 M)
833.3 μl of water (100 v/v)
D8
  • NDSB 221 BCC 0.5 M -
NA
333.3 μl of NDSB 221 BCC (1.5 M)
666.7 μl of water (100 v/v)
D9
  • NDSB 221 BCC 1 M -
NA
666.7 μl of NDSB 221 BCC (1.5 M)
333.3 μl of water (100 v/v)
D10
  • NDSB 256 BCC 0.25 M -
NA
166.7 μl of NDSB 256 BCC (1.5 M)
833.3 μl of water (100 v/v)
D11
  • NDSB 256 BCC 0.5 M -
NA
333.3 μl of NDSB 256 BCC (1.5 M)
666.7 μl of water (100 v/v)
D12
  • NDSB 256 BCC 1 M -
NA
666.7 μl of NDSB 256 BCC (1.5 M)
333.3 μl of water (100 v/v)
E1
  • sodium malonate-malonic acid BCC 0.5 M pH 7
pH 7
147.1 μl of sodium malonate-malonic acid BCC pH 7 (3.4 M)
852.9 μl of water (100 v/v)
E2
  • sodium malonate-malonic acid BCC 1 M pH 7
pH 7
294.1 μl of sodium malonate-malonic acid BCC pH 7 (3.4 M)
705.9 μl of water (100 v/v)
E3
  • sodium malonate-malonic acid BCC 1.5 M pH 7
pH 7
441.2 μl of sodium malonate-malonic acid BCC pH 7 (3.4 M)
558.8 μl of water (100 v/v)
E4
  • sodium succinate BCC 0.5 M -
NA
333.3 μl of sodium succinate BCC (1.5 M)
666.7 μl of water (100 v/v)
E5
  • sodium succinate BCC 1 M -
NA
666.7 μl of sodium succinate BCC (1.5 M)
333.3 μl of water (100 v/v)
E6
  • sodium succinate BCC 1.5 M -
NA
1000.0 μl of sodium succinate BCC (1.5 M)
E7
  • DL-malic acid BCC 0.25 M -
NA
250.0 μl of DL-malic acid BCC pH 7 (1 M)
750.0 μl of water (100 v/v)
E8
  • DL-malic acid BCC 0.5 M -
NA
500.0 μl of DL-malic acid BCC pH 7 (1 M)
500.0 μl of water (100 v/v)
E9
  • DL-malic acid BCC 1 M -
NA
1000.0 μl of DL-malic acid BCC pH 7 (1 M)
E10
  • potassium sodium phosphate BCC 0.5 M pH 7
pH 7
250.0 μl of potassium sodium phosphate BCC pH 7 (2 M)
750.0 μl of water (100 v/v)
E11
  • potassium sodium phosphate BCC 1 M pH 7
pH 7
500.0 μl of potassium sodium phosphate BCC pH 7 (2 M)
500.0 μl of water (100 v/v)
E12
  • potassium sodium phosphate BCC 2 M pH 7
pH 7
1000.0 μl of potassium sodium phosphate BCC pH 7 (2 M)
F1
  • sodium chloride BCC 0.5 M -
NA
500.0 μl of sodium chloride BCC (1 M)
500.0 μl of water (100 v/v)
F2
  • sodium chloride BCC 1 M -
NA
1000.0 μl of sodium chloride BCC (1 M)
F3
  • sodium chloride BCC 2 M -
NA
1000.0 μl of sodium chloride BCC (2 M)
F4
  • potassium chloride BCC 0.5 M -
NA
500.0 μl of potassium chloride BCC (1 M)
500.0 μl of water (100 v/v)
F5
  • potassium chloride BCC 1 M -
NA
1000.0 μl of potassium chloride BCC (1 M)
F6
  • potassium chloride BCC 2 M -
NA
666.7 μl of potassium chloride BCC (3 M)
333.3 μl of water (100 v/v)
F7
  • magnesium chloride BCC 0.5 M -
NA
500.0 μl of magnesium chloride BCC (1 M)
500.0 μl of water (100 v/v)
F8
  • magnesium chloride BCC 1 M -
NA
1000.0 μl of magnesium chloride BCC (1 M)
F9
  • magnesium chloride BCC 2 M -
NA
800.0 μl of magnesium chloride BCC (2.5 M)
200.0 μl of water (100 v/v)
F10
  • 1-butyl-3-methylimidazolium tetrafluoroborate BCC 4 w/v -
NA
80.0 μl of 1-butyl-3-methylimidazolium tetrafluoroborate BCC (50 w/v)
920.0 μl of water (100 v/v)
F11
  • 1-butyl-3-methylimidazolium tetrafluoroborate BCC 8 w/v -
NA
160.0 μl of 1-butyl-3-methylimidazolium tetrafluoroborate BCC (50 w/v)
840.0 μl of water (100 v/v)
F12
  • 1-butyl-3-methylimidazolium tetrafluoroborate BCC 20 w/v -
NA
400.0 μl of 1-butyl-3-methylimidazolium tetrafluoroborate BCC (50 w/v)
600.0 μl of water (100 v/v)
G1
  • sodium sulfate BCC 0.4 M -
NA
333.3 μl of sodium sulfate BCC (1.2 M)
666.7 μl of water (100 v/v)
G2
  • sodium sulfate BCC 0.8 M -
NA
666.7 μl of sodium sulfate BCC (1.2 M)
333.3 μl of water (100 v/v)
G3
  • sodium sulfate BCC 1.2 M -
NA
1000.0 μl of sodium sulfate BCC (1.2 M)
G4
  • sodium thiocyanate BCC 0.5 M -
NA
250.0 μl of sodium thiocyanate BCC (2 M)
750.0 μl of water (100 v/v)
G5
  • sodium thiocyanate BCC 1 M -
NA
500.0 μl of sodium thiocyanate BCC (2 M)
500.0 μl of water (100 v/v)
G6
  • sodium thiocyanate BCC 2 M -
NA
1000.0 μl of sodium thiocyanate BCC (2 M)
G7
  • sodium nitrate BCC 0.5 M -
NA
500.0 μl of sodium nitrate BCC (1 M)
500.0 μl of water (100 v/v)
G8
  • sodium nitrate BCC 1 M -
NA
1000.0 μl of sodium nitrate BCC (1 M)
G9
  • sodium nitrate BCC 2 M -
NA
285.7 μl of sodium nitrate BCC (7 M)
714.3 μl of water (100 v/v)
G10
  • dimethyl sulfoxide BCC 4 v/v -
NA
40.0 μl of dimethyl sulfoxide BCC (100 v/v)
960.0 μl of water (100 v/v)
G11
  • dimethyl sulfoxide BCC 8 v/v -
NA
80.0 μl of dimethyl sulfoxide BCC (100 v/v)
920.0 μl of water (100 v/v)
G12
  • dimethyl sulfoxide BCC 40 v/v -
NA
400.0 μl of dimethyl sulfoxide BCC (100 v/v)
600.0 μl of water (100 v/v)
H1NA
1000.0 μl of water (100 v/v)
H2NA
1000.0 μl of water (100 v/v)
H3NA
1000.0 μl of water (100 v/v)
H4
  • disodium EDTA BCC 0.05 M -
NA
100.0 μl of disodium EDTA BCC (0.5 M)
900.0 μl of water (100 v/v)
H5
  • disodium EDTA BCC 0.1 M -
NA
200.0 μl of disodium EDTA BCC (0.5 M)
800.0 μl of water (100 v/v)
H6
  • disodium EDTA BCC 0.2 M -
NA
400.0 μl of disodium EDTA BCC (0.5 M)
600.0 μl of water (100 v/v)
H7
  • trimethylamine N-oxide BCC 0.25 M -
NA
250.0 μl of trimethylamine N-oxide BCC (1 M)
750.0 μl of water (100 v/v)
H8
  • trimethylamine N-oxide BCC 0.5 M -
NA
500.0 μl of trimethylamine N-oxide BCC (1 M)
500.0 μl of water (100 v/v)
H9
  • trimethylamine N-oxide BCC 1 M -
NA
1000.0 μl of trimethylamine N-oxide BCC (1 M)
H10NA
1000.0 μl of water (100 v/v)
H11NA
1000.0 μl of water (100 v/v)
H12NA
1000.0 μl of water (100 v/v)