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Supplemental Information

Screen Description

Sol & Stab Screen

Hampton Research / Sol & Stab Screen
Created 2012-08-10.

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Sol & Stab Screen

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Screen Structure

Sol & Stab Screen

Well Count 96
Number of distinct ingredients 97
Internal diversity (score mean dist) 0.999

Screen Composition

2025-08-12T11:04:36.993129 image/svg+xml Matplotlib v3.10.5, https://matplotlib.org/
ingredient type Sol & Stab Screen
Buffer 11
Complex ingredient 1
Cryoprotectant 2
Detergent 5
Organic (non-volatile) 5
Polymer 7
Salt 25
Water 1

Well Contents

Buffers are shown in italics. More information about buffers.
Primary factors are shown in bold. More information about primary factors.
Sol & Stab Screen Well Contents  🔍
WellIngredient, Concentration, Units, pHpHRecipe 1000μl
A1
  • Water 100 v/v -
NA
1000.0 μl of Water (100 v/v)
A2
  • Trichloroacetic acid 75 w/v -
NA
750.0 μl of Trichloroacetic acid (100 w/v)
250.0 μl of water (100 v/v)
A3
  • L-Arginine 0.25 M -
NA
250.0 μl of L-Arginine (1 M)
750.0 μl of water (100 v/v)
A4
  • L-Arginine 0.25 M -
  • L-Glutamic acid 0.25 M -
NA
250.0 μl of L-Arginine (1 M)
250.0 μl of L-Glutamic acid (1 M)
500.0 μl of water (100 v/v)
A5
  • Glycine 0.5 M -
NA
500.0 μl of Glycine (1 M)
500.0 μl of water (100 v/v)
A6
  • L-Proline 0.5 M -
NA
500.0 μl of L-Proline (1 M)
500.0 μl of water (100 v/v)
A7
  • L-Histidine 0.12 M -
NA
120.0 μl of L-Histidine (1 M)
880.0 μl of water (100 v/v)
A8
  • ß-Alanine 0.5 M -
NA
500.0 μl of ß-Alanine (1 M)
500.0 μl of water (100 v/v)
A9
  • L-Serine 0.5 M -
NA
500.0 μl of L-Serine (1 M)
500.0 μl of water (100 v/v)
A10
  • L-Arginine ethyl ester dihydrochloride 0.5 M -
NA
500.0 μl of L-Arginine ethyl ester dihydrochloride (1 M)
500.0 μl of water (100 v/v)
A11
  • L-Argininamide dihydrochloride 0.5 M -
NA
500.0 μl of L-Argininamide dihydrochloride (1 M)
500.0 μl of water (100 v/v)
A12
  • 6-Aminohexanoic acid 0.5 M -
NA
500.0 μl of 6-Aminohexanoic acid (1 M)
500.0 μl of water (100 v/v)
B1
  • Glycyl-glycine 0.5 M -
NA
500.0 μl of Glycyl-glycine (1 M)
500.0 μl of water (100 v/v)
B2
  • Glycyl-glycyl-glycine 0.2 M -
NA
666.7 μl of Glycyl-glycyl-glycine (0.3 M)
333.3 μl of water (100 v/v)
B3
  • Tryptone 5 w/v -
NA
500.0 μl of Tryptone (10 w/v)
500.0 μl of water (100 v/v)
B4
  • Betaine 2.5 M -
NA
1000.0 μl of Betaine (2.5 M)
B5
  • D-(+)-Trehalose 0.75 M -
NA
750.0 μl of D-(+)-Trehalose (1 M)
250.0 μl of water (100 v/v)
B6
  • Xylitol 2 M -
NA
1000.0 μl of Xylitol (2 M)
B7
  • D-Sorbitol 2 M -
NA
1000.0 μl of D-Sorbitol (2 M)
B8
  • D-(+)-Sucrose 2 M -
NA
1000.0 μl of D-(+)-Sucrose (2 M)
B9
  • Hydroxyectoine 0.5 M -
NA
500.0 μl of Hydroxyectoine (1 M)
500.0 μl of water (100 v/v)
B10
  • Trimethylamine N-oxide 2.5 M -
NA
1000.0 μl of Trimethylamine N-oxide (2.5 M)
B11
  • Methyl-a-D-glucoside 2 M -
NA
1000.0 μl of Methyl-a-D-glucoside (2 M)
B12
  • Triethylene glycol 10 v/v -
NA
100.0 μl of Triethylene glycol (100 v/v)
900.0 μl of water (100 v/v)
C1
  • Spermine Tetrahydrochloride 500 mM -
NA
1000.0 μl of Spermine Tetrahydrochloride (500 mM)
C2
  • Spermine Tetrahydrochloride 500 mM -
NA
1000.0 μl of Spermine Tetrahydrochloride (500 mM)
C3
  • 5-Aminovaleric acid 0.5 M -
NA
500.0 μl of 5-Aminovaleric acid (1 M)
500.0 μl of water (100 v/v)
C4
  • Glutaric acid 0.5 M -
NA
500.0 μl of Glutaric acid (1 M)
500.0 μl of water (100 v/v)
C5
  • Adipic acid 80 mM -
NA
800.0 μl of Adipic acid (100 mM)
200.0 μl of water (100 v/v)
C6
  • Ethylenediamine dihydrochloride 0.5 M -
NA
500.0 μl of Ethylenediamine dihydrochloride (1 M)
500.0 μl of water (100 v/v)
C7
  • Guanidine hydrochloride 0.5 M -
NA
500.0 μl of Guanidine hydrochloride (1 M)
500.0 μl of water (100 v/v)
C8
  • Urea 0.5 M -
NA
250.0 μl of Urea (2 M)
750.0 μl of water (100 v/v)
C9
  • N-Methylurea 0.5 M -
NA
500.0 μl of N-Methylurea (1 M)
500.0 μl of water (100 v/v)
C10
  • N-Ethylurea 0.2 M -
NA
200.0 μl of N-Ethylurea (1 M)
800.0 μl of water (100 v/v)
C11
  • N-Methylformamide 30 w/v -
NA
1000.0 μl of N-Methylformamide (30 w/v)
C12
  • 2-Aminoethanesulfinic acid 3 w/v -
NA
300.0 μl of 2-Aminoethanesulfinic acid (10 w/v)
700.0 μl of water (100 v/v)
D1
  • Tris(2-carboxyethyl)phosphine hydrochloride 0.1 M -
NA
100.0 μl of Tris(2-carboxyethyl)phosphine hydrochloride (1 M)
900.0 μl of water (100 v/v)
D2
  • L-Glutathione reduced, L-Glutathione oxidized 10 mM -
NA
1000.0 μl of L-Glutathione reduced, L-Glutathione oxidized (10 mM)
D3
  • Benzamidine hydrochloride 5 w/v -
NA
250.0 μl of Benzamidine hydrochloride (20 w/v)
750.0 μl of water (100 v/v)
D4
  • Ethylenediaminetetraacetic acid disodium salt 0.1 M -
NA
1000.0 μl of Ethylenediaminetetraacetic acid disodium salt (0.1 M)
D5
  • Magnesium chloride 0.1 M -
  • Calcium chloride 0.1 M -
NA
50.0 μl of Calcium chloride (2 M)
50.0 μl of Magnesium chloride (2 M)
900.0 μl of water (100 v/v)
D6
  • Cadmium chloride 0.1 M -
  • Cobalt (II) chloride 0.1 M -
NA
100.0 μl of Cadmium chloride (1 M)
100.0 μl of Cobalt (II) chloride (1 M)
800.0 μl of water (100 v/v)
D7
  • Non-Detergent Sulfobetaine (NDSB) 195 1 M -
NA
333.3 μl of Non-Detergent Sulfobetaine (NDSB) 195 (3 M)
666.7 μl of water (100 v/v)
D8
  • Non-Detergent Sulfobetaine (NDSB) 201 1 M -
NA
500.0 μl of Non-Detergent Sulfobetaine (NDSB) 201 (2 M)
500.0 μl of water (100 v/v)
D9
  • Non-Detergent Sulfobetaine (NDSB) 211 1 M -
NA
500.0 μl of Non-Detergent Sulfobetaine (NDSB) 211 (2 M)
500.0 μl of water (100 v/v)
D10
  • Non-Detergent Sulfobetaine (NDSB) 221 1 M -
NA
500.0 μl of Non-Detergent Sulfobetaine (NDSB) 221 (2 M)
500.0 μl of water (100 v/v)
D11
  • Non-Detergent Sulfobetaine (NDSB) 256 1 M -
NA
1000.0 μl of Non-Detergent Sulfobetaine (NDSB) 256 (1 M)
D12
  • 2-Aminoethanesulfonic acid 0.5 M -
NA
500.0 μl of 2-Aminoethanesulfonic acid (1 M)
500.0 μl of water (100 v/v)
E1
  • Acetamide 0.5 M -
NA
500.0 μl of Acetamide (1 M)
500.0 μl of water (100 v/v)
E2
  • Oxalic acid 0.5 M -
NA
500.0 μl of Oxalic acid (1 M)
500.0 μl of water (100 v/v)
E3
  • di-Sodium malonate 0.5 M -
NA
147.1 μl of di-Sodium malonate pH 7 (3.4 M)
852.9 μl of water (100 v/v)
E4
  • di-Sodium succinate 0.5 M -
NA
500.0 μl of di-Sodium succinate pH 7 (1 M)
500.0 μl of water (100 v/v)
E5
  • Tacsimate 5 v/v -
NA
50.0 μl of Tacsimate pH 7 (100 v/v)
950.0 μl of water (100 v/v)
E6
  • Tetraethylammonium bromide 25 w/v -
NA
500.0 μl of Tetraethylammonium bromide (50 w/v)
500.0 μl of water (100 v/v)
E7
  • Choline acetate 25 w/v -
NA
500.0 μl of Choline acetate (50 w/v)
500.0 μl of water (100 v/v)
E8
  • 1-Ethyl-3-methylimidazolium acetate 25 w/v -
NA
500.0 μl of 1-Ethyl-3-methylimidazolium acetate (50 w/v)
500.0 μl of water (100 v/v)
E9
  • 1-Butyl-3-methylimidazolium chloride 25 w/v -
NA
500.0 μl of 1-Butyl-3-methylimidazolium chloride (50 w/v)
500.0 μl of water (100 v/v)
E10
  • Ethylammonium nitrate 25 w/v -
NA
500.0 μl of Ethylammonium nitrate (50 w/v)
500.0 μl of water (100 v/v)
E11
  • Ammonium sulfate 0.5 M -
NA
142.9 μl of Ammonium sulfate (3.5 M)
857.1 μl of water (100 v/v)
E12
  • Ammonium chloride 0.5 M -
NA
100.0 μl of Ammonium chloride (5 M)
900.0 μl of water (100 v/v)
F1
  • Magnesium sulfate 0.5 M -
NA
250.0 μl of Magnesium sulfate (2 M)
750.0 μl of water (100 v/v)
F2
  • Potassium thiocyanate 0.5 M -
NA
62.5 μl of Potassium thiocyanate (8 M)
937.5 μl of water (100 v/v)
F3
  • Gadolinium (III) chloride 250 mM -
NA
500.0 μl of Gadolinium (III) chloride (500 mM)
500.0 μl of water (100 v/v)
F4
  • Cesium chloride 0.25 M -
NA
250.0 μl of Cesium chloride (1 M)
750.0 μl of water (100 v/v)
F5
  • 4-Aminobutyric acid 250 mM -
NA
500.0 μl of 4-Aminobutyric acid (500 mM)
500.0 μl of water (100 v/v)
F6
  • Lithium nitrate 0.5 M -
NA
62.5 μl of Lithium nitrate (8 M)
937.5 μl of water (100 v/v)
F7
  • di-Sodium DL-malate 0.5 M -
NA
166.7 μl of di-Sodium DL-malate pH 7 (3 M)
833.3 μl of water (100 v/v)
F8
  • tri-Lithium citrate 0.5 M -
NA
333.3 μl of tri-Lithium citrate (1.5 M)
666.7 μl of water (100 v/v)
F9
  • Ammonium acetate 0.25 M -
NA
250.0 μl of Ammonium acetate (1 M)
750.0 μl of water (100 v/v)
F10
  • Sodium benzenesulfonate 250 mM -
NA
500.0 μl of Sodium benzenesulfonate (500 mM)
500.0 μl of water (100 v/v)
F11
  • Sodium p-toluenesulfonate 250 mM -
NA
500.0 μl of Sodium p-toluenesulfonate (500 mM)
500.0 μl of water (100 v/v)
F12
  • Sodium chloride 1 M -
NA
200.0 μl of Sodium chloride (5 M)
800.0 μl of water (100 v/v)
G1
  • Potassium chloride 1 M -
NA
250.0 μl of Potassium chloride (4 M)
750.0 μl of water (100 v/v)
G2
  • di-Sodium hydrogen phosphate 0.7 M -
  • Potassium di-hydrogen phosphate 1.3 M -
NA
325.0 μl of Potassium di-hydrogen phosphate (4 M)
175.0 μl of di-Sodium hydrogen phosphate (4 M)
500.0 μl of water (100 v/v)
G3
  • Sodium sulfate 1 M -
NA
1000.0 μl of Sodium sulfate (1 M)
G4
  • Lithium chloride 1 M -
NA
100.0 μl of Lithium chloride (10 M)
900.0 μl of water (100 v/v)
G5
  • Sodium bromide 1 M -
NA
200.0 μl of Sodium bromide (5 M)
800.0 μl of water (100 v/v)
G6
  • Glycerol 40 v/v -
  • Lithium chloride 0.4 M -
NA
400.0 μl of Glycerol (100 v/v)
40.0 μl of Lithium chloride (10 M)
560.0 μl of water (100 v/v)
G7
  • Glycerol 50 v/v -
NA
500.0 μl of Glycerol (100 v/v)
500.0 μl of water (100 v/v)
G8
  • Ethylene glycol 10 v/v -
NA
100.0 μl of Ethylene glycol (100 v/v)
900.0 μl of water (100 v/v)
G9
  • Polyethylene glycol 200 10 v/v -
NA
100.0 μl of Polyethylene glycol 200 (100 v/v)
900.0 μl of water (100 v/v)
G10
  • Polyethylene glycol monomethyl ether 550 5 v/v -
NA
50.0 μl of Polyethylene glycol monomethyl ether 550 (100 v/v)
950.0 μl of water (100 v/v)
G11
  • Polyethylene glycol monomethyl ether 750 5 v/v -
NA
100.0 μl of Polyethylene glycol monomethyl ether 750 (50 v/v)
900.0 μl of water (100 v/v)
G12
  • Formamide 50 v/v -
NA
1000.0 μl of Formamide (50 v/v)
H1
  • Polypropylene glycol 400 50 v/v -
NA
500.0 μl of Polypropylene glycol 400 (100 v/v)
500.0 μl of water (100 v/v)
H2
  • Pentaerythritol ethoxylate (15/4 EO/OH) 25 v/v -
NA
500.0 μl of Pentaerythritol ethoxylate (15/4 EO/OH) (50 v/v)
500.0 μl of water (100 v/v)
H3
  • 1,2-Propanediol 10 v/v -
NA
100.0 μl of 1,2-Propanediol (100 v/v)
900.0 μl of water (100 v/v)
H4
  • Polyethylene glycol monomethyl ether 1,900 3 w/v -
NA
60.0 μl of Polyethylene glycol monomethyl ether 1,900 (50 w/v)
940.0 μl of water (100 v/v)
H5
  • Polyethylene glycol 3,350 3 w/v -
NA
60.0 μl of Polyethylene glycol 3,350 (50 w/v)
940.0 μl of water (100 v/v)
H6
  • Polyethylene glycol 8,000 3 w/v -
NA
60.0 μl of Polyethylene glycol 8,000 (50 w/v)
940.0 μl of water (100 v/v)
H7
  • Polyvinylpyrrolidone K15 2 w/v -
NA
40.0 μl of Polyvinylpyrrolidone K15 (50 w/v)
960.0 μl of water (100 v/v)
H8
  • 6-O-a-Maltosyl-ß-cyclodextrin 100 mM -
NA
1000.0 μl of 6-O-a-Maltosyl-ß-cyclodextrin (100 mM)
H9
  • 2-hydroxypropyl-ß-cyclodextrin 10 mM -
NA
200.0 μl of 2-hydroxypropyl-ß-cyclodextrin (50 mM)
800.0 μl of water (100 v/v)
H10
  • a-Cyclodextrin 80 mM -
NA
800.0 μl of a-Cyclodextrin (100 mM)
200.0 μl of water (100 v/v)
H11
  • ß-cyclodextrin 10 mM -
NA
100.0 μl of ß-cyclodextrin (100 mM)
900.0 μl of water (100 v/v)
H12
  • Methyl-ß-cyclodextrin 50 mM -
NA
500.0 μl of Methyl-ß-cyclodextrin (100 mM)
500.0 μl of water (100 v/v)